Le 15/10/2021 de 13:30 à 15:30

Retour Session


Analyse en situation écologique des activations cérébrales du cortex moteur pendant des tâches unimanuelles de poursuite de trajectoire et de saisie

Camille O. Muller (Montpellier, France), Karima K.A. Bakhti (Montpellier, France), Makii Muthalib (Montpellier, France), Denis Mottet (Montpellier, France), Stéphane Perrey (Montpellier, France), Isabelle Laffont (Montpellier, France)

Objective : After a stroke, brain activation reorganisation and its evolution through rehabilitation is a subject of major interest. Two non-invasive neuroimaging methods allow for recording the task-related brain activation in ecological settings for bedside monitoring: functional near-infrared spectroscopy (fNIRS) and functional electroencephalography (fEEG) respectively based on cerebral haemodynamic response and electrical activity. Their simultaneous use allows for an integrated spatiotemporal mapping of the movement-related brain activity to unveil underlying mechanisms of functional upper limb (UL) recovery during rehabilitation. First, we aim to depict reference activation patterns of the motor cortices in healthy using fNIRS-fEEG and their association with the motor performance during UL functional tasks.

Material / Patients and Methods : Healthy participants without UL and neurological impairment realized two seated-functional UL tasks. They had to reach a target in front of them and then to steer a cursor within a circular path focusing on speed over accuracy. Simultaneously, UL kinematics and activation of the motor cortices, using fNIRS-fEEG, were recorded.

Results : With 20 subjects we found that combined fNIRS-fEEG allows to explore motor cortex activation during UL movements providing greater information than each method alone. FNIRS-fEEG signal analyses confirmed the greater contralateral brain activation and showed that event-related desynchronization of the Mu-Beta rhythm were mainly present during active periods compared to rest periods.

Discussion - Conclusion : We confirmed that combined fNIRS-fEEG in healthy people can describe brain activation during functional UL movements. The next step is to apply this method at the bedside in rehabilitation units to improve our knowledge of brain plasticity after stroke and its evolution under rehabilitation.  

Keywords : functionnal tasks; functionnal neuroimagery; fEEG; fNIRS; stroke; rehabilitation