Communication Affichée: Poster Tour 1

Le 14/10/2021 de 11:00 à 11:30

Retour Session


Vieillissement cognitif physiologique et mouvements binoculaires dans l’espace 3D

Zoï Kapoula (paris, France), Martin Chavant (paris, France)

Objective : The visual exploration of the 3D world is done through saccades and vergence eye movements. Their programming and execution involves an extensive cortical-subcortical circuit. This study investigates  the aging of eye movements and their link with cognition.

Material / Patients and Methods : 27 young people (mean age 25.7 + - 2.5) and 65 seniors (mean age 66.1 + - 8.5) participated in the study; no participant presented with pathology. Horizontal saccades (20 °), vergences (8.76 ° convergence and 6.5 ° divergence) were tested with the visual targets of the REMOBI & AIDEAL® device and the Pupil Labs® eye-tracker. Cognition was tested with the French version of Stroop Victoria (f-SV).

Results : The latencies were significantly longer for the vergences than for the saccades. With age the latency of all movements slowed significantly. In contrast, peak velocity remained unchanged while average velocity decreased with age. This indicates normal acceleration of movement of the eyes but slow deceleration due to age. The Stroop was showing normal scores for all participants. Reading time on the Stroop test remained unchanged with age; in contrast, the time on the cognitive interference tasks of the Stroop test correlated positively with age (longer interference time with age). More important, the interference time on the Stroop test positively correlated with saccade or convergence latency (the longer the eye movement latency the longer the stroop interference time).

Discussion - Conclusion : The physiological aging of eye movements is selective  affecting mainly the latency which depends on the cerebral circuits. Eye movement latency is a compact executive cognitive function. It offers an easy tool to regularly quantify physiological cognitive aging and eventual deviations.

Keywords : Saccades, Verrgence Eye Movements, Cognitive Executive Functions, Ageing

Disclosure of interest : The study provides reference data on physiologic ageing of eye movements. Their latency being correlated to cognitive executive functions.  Eye movements could be used to evaluate regurlarly cognitive executive ffunctions. In clinic this type of data could be of maijor interest for early detection of deviation from normal, as it is the case for moderate cognitive impairement