Le 15/10/2021 de 11:00 à 12:30

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Evaluation cognitive à 6 mois d'une infection à SARS-Cov2

Amandine Rapin (Reims, France), Arnaud Calmus (Reims, France), Sandy Carazo-Mendez (Reims, France), François Constant Boyer (Reims, France)

Objective : Due to several physiopathological mechanisms, cognitive impairment are expected and reported by patients after SARS-Cov2 infection. The aim of this work is to objective this impairment.

Material / Patients and Methods : We realized a cross sectional study from September the 1rst to December the 18th in 2020 in patients addressed in Physical and medicine and rehabilitation (PMR) unit for post COVID complains. Memory was assessed by direct and visual span, working memory by the working memory index in the WAIS-IV, processing speed by the processing speed index in the WAIS-IV and attention by the alertness test in the battery for attention testing (TAP). Fatigue and anxiety-depression was research by questionnaires.

Results : Sixty-eight patients received the test whose 37 with cognitive complains. In the total population, abnormal score was found in 19% for processing speed index, 19% for direct span and 20,5% for visual span, 19% for working memory index, 30,9% for the TAP without warning test and 39,7% for the TAP with warning. Comparison of patient with and without complains does not show any difference in population characteristics (especially age and education level) and cognitive test results, but had more anxiety, depression and fatigue reports.

Discussion - Conclusion : Prevalence of cognitive impairment seems to be more important in this population. Limits are the absence of control group and the lack of information on previous cognitive level. 
Depression, anxiety and fatigue perception seems to impact the cognitive abilities perception.

Keywords : Cognitive dysfunction, SARS-Cov2, COVID-19, anxiety, depression

Disclosure of interest : Aucun